State-run media say Bashar Assad will talk about "domestic issues" and regional developments.
Assad has made few public appearances since the anti-government uprising began in March. The regime’s crackdown on dissent has killed thousands and led to international isolation and sanctions.
Syria agreed in December to the Arab-brokered plan that calls for an end to the military crackdown on protesters, but killings have continued. About 165 Arab League monitors are in Syria to determine whether the regime is abiding by the plan to stop violence and pull heavy weapons out of the cities.