An overnight Russian drone attack on Ukraine's second-largest city Kharkiv killed six people and wounded 10 others, national emergency services and the city's mayor said Saturday.

The State Emergency Service of Ukraine said in a Telegram post that "six people were killed and at least 10 injured as a result of an enemy strike".

Kharkiv mayor Igor Terekhov gave the same death toll and number of injured in a Telegram post, adding the attack had targeted Shevchenkivskyi, a northern area of the city.

Terekhov said Iranian-made drones had carried out the attack, hitting at least nine high-rise buildings, three dormitories and a petrol station.

Oleg Synegubov, the region's governor, said earlier two men were killed in Shevchenkivskyi.

Police confirmed the deaths and said a further eight people were hospitalised "with blast injuries and shrapnel wounds".

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"Among the wounded are two women aged 25 and 52, and six men aged 23 to 76," police said.

Police added that there were no casualties in a separate attack on Mala Danylivka, a village on Kharkiv's northwest outskirts.

Photos released by police on Telegram showed several fires in civilian areas, including near a high-rise apartment building.

Authorities said several buildings were damaged in the attack, including residential blocks and a petrol station.

The attack came as Ukraine's air force reported multiple groups of Russian drones across the country.

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